MicroRNAs and STAT interplay
نویسندگان
چکیده
منابع مشابه
Two host microRNAs influence WSSV replication via STAT gene regulation.
MicroRNAs (miRNAs) have important roles in post-transcriptional regulation of gene expression. During viral infection, viruses utilize hosts to enhance their replication by altering cellular miRNAs. The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway plays crucial roles in the antiviral responses. In this study, two miRNAs (miR-9041 and miR-9850) from Macrobra...
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Using microRNA array analyses of in vitro HIV-1-infected CD4(+) cells, we find that several host microRNAs are significantly up- or downregulated around the time HIV-1 infection peaks in vitro. While microRNA-223 levels were significantly enriched in HIV-1-infected CD4(+)CD8(-) PBMCs, microRNA-29a/b, microRNA-155 and microRNA-21 levels were significantly reduced. Based on the potential for micr...
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ژورنال
عنوان ژورنال: Seminars in Cancer Biology
سال: 2012
ISSN: 1044-579X
DOI: 10.1016/j.semcancer.2011.12.010